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人染色體核型基礎(chǔ)(醫(yī)學基礎(chǔ))

 vqgjd9 2018-09-25

1、染色體數(shù)目和形態(tài)

在人染色體核型圖的組成中,常染色體依照長度從長到短的順序用數(shù)字1到22表示,性染色體用X和Y表示。

根據(jù)染色體大小遞減的順序和著絲粒的位置,可將所有染色體分為七組(A—G)。

分組號

染色體號

形態(tài)大小

著絲粒位置

隨體

次縊痕

A

1—3

最大

近中部著絲粒

常見于1號

B

4—5

次大

亞中部著絲粒


C

6—12+X

中等

亞中部著絲粒

常見于9號

D

13—15

中等

頂端著絲粒

偏見13號

E

16—18

較小

近中部著絲粒

常見16號

F

19—20

次小

近中部著絲粒


G

21—22+y

最?。╕有變異)

頂端著絲粒

(Y無)


2、區(qū)、帶、亞帶的命名

G帶:也叫G顯帶,這是臨床上最常用的顯帶方法。用胰酶,緩沖液處理中期染色體標本均可顯帶。一般沿著染色體的臂從著絲粒開始向遠端開始標記區(qū)和帶。p和q分別用于表示染色體的短臂和長臂,著絲粒區(qū)定義為1區(qū)0帶,即為10;向著短臂部分稱為p10,面向長臂的部分稱為q10。每條臂上與著絲粒相連的部分定義為1,稍遠的區(qū)定義為2,依次類推。

一個特定的帶通常包含下面四個部分:(1)染色體號,(2)臂的符號,(3)區(qū)號,(4)該帶在所屬區(qū)的帶號。這四部分需要連續(xù)列出,中間不要有空格和間斷。例如1p31表示1號染色體短臂3區(qū)1帶。

亞帶命名示例為1p31.1,1p32.2和1p31.3,1p31.1靠近著絲粒,1p31.3遠離著絲粒,如果亞帶再予以分割,則只附加數(shù)字,中間不插入標記,如1p31.1可進一步分割為1p31.11, 1p31.12等,盡管在理論上,一條帶任何時候可分割任意數(shù)目的新帶,但通常一條帶只分割為三條亞帶。

人基因組總共劃分了862個區(qū)帶,每個帶的位置見下文附表。

3、符號和簡寫術(shù)語

下表列出所有用來描述染色體和染色體畸變的符號和簡寫術(shù)語。

add

額外未知起源的物質(zhì)

方括號[ ]

描述細胞數(shù)目

cen

著絲粒

chr

染色體

del

缺失

der

衍生染色體

dup

重復

h

異染色質(zhì)

ins

插入

inv

倒位

mar

標記染色體

mat

母方起源

減號

丟失

mos

嵌合體

p

染色體短臂

pat

父親起源

+(加號)

獲得

q

染色體長臂

qs

染色體長臂上的隨體

?(問號)

對某一染色或染色體結(jié)構(gòu)的疑問

r

環(huán)狀染色體

rob

羅賓遜易位

s

隨體

t

易位

ter

末端(染色體末端)

4、正常變異染色體的特征

4.1異染色區(qū),隨體柄和隨體的變異

4.1.1長度的變異

通過在相應染色體或其臂描述的符號h, stk, s之后加上“+”或“-”號,可以將異染色質(zhì)片段,隨體柄或隨體長度變異和由于其它結(jié)構(gòu)變異導致的染色體臂的長度的增減區(qū)分開來。

16qh+ 16號染色體長臂的異染色質(zhì)區(qū)長度的增加

Yqh- Y染色體長臂異染色質(zhì)區(qū)長度的減少

21ps+ 21號染色體短臂的隨體長度增加

22pstk+ 22號染色體短臂的隨體柄長度增加

13cenh+pat 13號染色體的著絲粒區(qū)的異染色質(zhì)長度增加,父系遺傳

1qh-, 13cenh+, 22ps+ 1號染色體長臂異染色質(zhì)長度減少,13號染色體著絲粒的異染色質(zhì)長度的增加,以及22號染色體大隨體。

15cenh+mat 15ps+pat 15號染色體著絲粒區(qū)異染色質(zhì)長度增加,母系遺傳,以及由父親遺傳而來的15號染色體大隨體。

14cenh+pstk+ps+ 14號染色體著絲粒區(qū)異染色質(zhì)長度,隨體柄和隨體長度的增加。

4.1.2數(shù)目和位置的變異

可用與上述相同的命名符號描述異染色質(zhì)區(qū),隨體柄和隨體的多樣性

17ps 17號染色體短臂的隨體

Yqs Y染色體長臂的隨體

9phqh 9號染色體長臂和短臂的異染色質(zhì)

9ph 9號染色體短臂的異染色質(zhì)

1q41h 1號染色體短臂4區(qū)1帶的異染色質(zhì)

通過重復相應結(jié)構(gòu)的描寫可用于表示重復的染色體結(jié)構(gòu)。

21pss 21號染色體短臂的雙隨體

14pstkstk 14號染色體短臂的雙隨體柄

相對而言,普通人群的倒位多樣性由其常染色質(zhì)的斷裂位點來決定。

inv(9)(p12q13) 9號染色體的臂間倒位

inv(2)(p11.2q13) 2號染色體的臂間倒位

5、附表每個區(qū)帶位置

chr102,300,000p36.33
chr12,300,0005,400,000p36.32
chr15,400,0007,200,000p36.31
chr17,200,0009,200,000p36.23
chr19,200,00012,700,000p36.22
chr112,700,00016,200,000p36.21
chr116,200,00020,400,000p36.13
chr120,400,00023,900,000p36.12
chr123,900,00028,000,000p36.11
chr128,000,00030,200,000p35.3
chr130,200,00032,400,000p35.2
chr132,400,00034,600,000p35.1
chr134,600,00040,100,000p34.3
chr140,100,00044,100,000p34.2
chr144,100,00046,800,000p34.1
chr146,800,00050,700,000p33
chr150,700,00056,100,000p32.3
chr156,100,00059,000,000p32.2
chr159,000,00061,300,000p32.1
chr161,300,00068,900,000p31.3
chr168,900,00069,700,000p31.2
chr169,700,00084,900,000p31.1
chr184,900,00088,400,000p22.3
chr188,400,00092,000,000p22.2
chr192,000,00094,700,000p22.1
chr194,700,00099,700,000p21.3
chr199,700,000102,200,000p21.2
chr1102,200,000107,200,000p21.1
chr1107,200,000111,800,000p13.3
chr1111,800,000116,100,000p13.2
chr1116,100,000117,800,000p13.1
chr1117,800,000120,600,000p12
chr1120,600,000121,500,000p11.2
chr1121,500,000125,000,000p11.1
chr1125,000,000128,900,000q11
chr1128,900,000142,600,000q12
chr1142,600,000147,000,000q21.1
chr1147,000,000150,300,000q21.2
chr1150,300,000155,000,000q21.3
chr1155,000,000156,500,000q22
chr1156,500,000159,100,000q23.1
chr1159,100,000160,500,000q23.2
chr1160,500,000165,500,000q23.3
chr1165,500,000167,200,000q24.1
chr1167,200,000170,900,000q24.2
chr1170,900,000172,900,000q24.3
chr1172,900,000176,000,000q25.1
chr1176,000,000180,300,000q25.2
chr1180,300,000185,800,000q25.3
chr1185,800,000190,800,000q31.1
chr1190,800,000193,800,000q31.2
chr1193,800,000198,700,000q31.3
chr1198,700,000207,200,000q32.1
chr1207,200,000211,500,000q32.2
chr1211,500,000214,500,000q32.3
chr1214,500,000224,100,000q41
chr1224,100,000224,600,000q42.11
chr1224,600,000227,000,000q42.12
chr1227,000,000230,700,000q42.13
chr1230,700,000234,700,000q42.2
chr1234,700,000236,600,000q42.3
chr1236,600,000243,700,000q43
chr1243,700,000249,250,621q44
chr1003,000,000p15.3
chr103,000,0003,800,000p15.2
chr103,800,0006,600,000p15.1
chr106,600,00012,200,000p14
chr1012,200,00017,300,000p13
chr1017,300,00018,600,000p12.33
chr1018,600,00018,700,000p12.32
chr1018,700,00022,600,000p12.31
chr1022,600,00024,600,000p12.2
chr1024,600,00029,600,000p12.1
chr1029,600,00031,300,000p11.23
chr1031,300,00034,400,000p11.22
chr1034,400,00038,000,000p11.21
chr1038,000,00040,200,000p11.1
chr1040,200,00042,300,000q11.1
chr1042,300,00046,100,000q11.21
chr1046,100,00049,900,000q11.22
chr1049,900,00052,900,000q11.23
chr1052,900,00061,200,000q21.1
chr1061,200,00064,500,000q21.2
chr1064,500,00070,600,000q21.3
chr1070,600,00074,900,000q22.1
chr1074,900,00077,700,000q22.2
chr1077,700,00082,000,000q22.3
chr1082,000,00087,900,000q23.1
chr1087,900,00089,500,000q23.2
chr1089,500,00092,900,000q23.31
chr1092,900,00094,100,000q23.32
chr1094,100,00097,000,000q23.33
chr1097,000,00099,300,000q24.1
chr1099,300,000101,900,000q24.2
chr10101,900,000103,000,000q24.31
chr10103,000,000104,900,000q24.32
chr10104,900,000105,800,000q24.33
chr10105,800,000111,900,000q25.1
chr10111,900,000114,900,000q25.2
chr10114,900,000119,100,000q25.3
chr10119,100,000121,700,000q26.11
chr10121,700,000123,100,000q26.12
chr10123,100,000127,500,000q26.13
chr10127,500,000130,600,000q26.2
chr10130,600,000135,534,747q26.3
chr1102,800,000p15.5
chr112,800,00010,700,000p15.4
chr1110,700,00012,700,000p15.3
chr1112,700,00016,200,000p15.2
chr1116,200,00021,700,000p15.1
chr1121,700,00026,100,000p14.3
chr1126,100,00027,200,000p14.2
chr1127,200,00031,000,000p14.1
chr1131,000,00036,400,000p13
chr1136,400,00043,500,000p12
chr1143,500,00048,800,000p11.2
chr1148,800,00051,600,000p11.12
chr1151,600,00053,700,000p11.11
chr1153,700,00055,700,000q11
chr1155,700,00059,900,000q12.1
chr1159,900,00061,700,000q12.2
chr1161,700,00063,400,000q12.3
chr1163,400,00065,900,000q13.1
chr1165,900,00068,400,000q13.2
chr1168,400,00070,400,000q13.3
chr1170,400,00075,200,000q13.4
chr1175,200,00077,100,000q13.5
chr1177,100,00085,600,000q14.1
chr1185,600,00088,300,000q14.2
chr1188,300,00092,800,000q14.3
chr1192,800,00097,200,000q21
chr1197,200,000102,100,000q22.1
chr11102,100,000102,900,000q22.2
chr11102,900,000110,400,000q22.3
chr11110,400,000112,500,000q23.1
chr11112,500,000114,500,000q23.2
chr11114,500,000121,200,000q23.3
chr11121,200,000123,900,000q24.1
chr11123,900,000127,800,000q24.2
chr11127,800,000130,800,000q24.3
chr11130,800,000135,006,516q25
chr1203,300,000p13.33
chr123,300,0005,400,000p13.32
chr125,400,00010,100,000p13.31
chr1210,100,00012,800,000p13.2
chr1212,800,00014,800,000p13.1
chr1214,800,00020,000,000p12.3
chr1220,000,00021,300,000p12.2
chr1221,300,00026,500,000p12.1
chr1226,500,00027,800,000p11.23
chr1227,800,00030,700,000p11.22
chr1230,700,00033,300,000p11.21
chr1233,300,00035,800,000p11.1
chr1235,800,00038,200,000q11
chr1238,200,00046,400,000q12
chr1246,400,00049,100,000q13.11
chr1249,100,00051,500,000q13.12
chr1251,500,00054,900,000q13.13
chr1254,900,00056,600,000q13.2
chr1256,600,00058,100,000q13.3
chr1258,100,00063,100,000q14.1
chr1263,100,00065,100,000q14.2
chr1265,100,00067,700,000q14.3
chr1267,700,00071,500,000q15
chr1271,500,00075,700,000q21.1
chr1275,700,00080,300,000q21.2
chr1280,300,00086,700,000q21.31
chr1286,700,00089,000,000q21.32
chr1289,000,00092,600,000q21.33
chr1292,600,00096,200,000q22
chr1296,200,000101,600,000q23.1
chr12101,600,000103,800,000q23.2
chr12103,800,000109,000,000q23.3
chr12109,000,000111,700,000q24.11
chr12111,700,000112,300,000q24.12
chr12112,300,000114,300,000q24.13
chr12114,300,000116,800,000q24.21
chr12116,800,000118,100,000q24.22
chr12118,100,000120,700,000q24.23
chr12120,700,000125,900,000q24.31
chr12125,900,000129,300,000q24.32
chr12129,300,000133,851,895q24.33
chr1304,500,000p13
chr134,500,00010,000,000p12
chr1310,000,00016,300,000p11.2
chr1316,300,00017,900,000p11.1
chr1317,900,00019,500,000q11
chr1319,500,00023,300,000q12.11
chr1323,300,00025,500,000q12.12
chr1325,500,00027,800,000q12.13
chr1327,800,00028,900,000q12.2
chr1328,900,00032,200,000q12.3
chr1332,200,00034,000,000q13.1
chr1334,000,00035,500,000q13.2
chr1335,500,00040,100,000q13.3
chr1340,100,00045,200,000q14.11
chr1345,200,00045,800,000q14.12
chr1345,800,00047,300,000q14.13
chr1347,300,00050,900,000q14.2
chr1350,900,00055,300,000q14.3
chr1355,300,00059,600,000q21.1
chr1359,600,00062,300,000q21.2
chr1362,300,00065,700,000q21.31
chr1365,700,00068,600,000q21.32
chr1368,600,00073,300,000q21.33
chr1373,300,00075,400,000q22.1
chr1375,400,00077,200,000q22.2
chr1377,200,00079,000,000q22.3
chr1379,000,00087,700,000q31.1
chr1387,700,00090,000,000q31.2
chr1390,000,00095,000,000q31.3
chr1395,000,00098,200,000q32.1
chr1398,200,00099,300,000q32.2
chr1399,300,000101,700,000q32.3
chr13101,700,000104,800,000q33.1
chr13104,800,000107,000,000q33.2
chr13107,000,000110,300,000q33.3
chr13110,300,000115,169,878q34
chr1403,700,000p13
chr143,700,0008,100,000p12
chr148,100,00016,100,000p11.2
chr1416,100,00017,600,000p11.1
chr1417,600,00019,100,000q11.1
chr1419,100,00024,600,000q11.2
chr1424,600,00033,300,000q12
chr1433,300,00035,300,000q13.1
chr1435,300,00036,600,000q13.2
chr1436,600,00037,800,000q13.3
chr1437,800,00043,500,000q21.1
chr1443,500,00047,200,000q21.2
chr1447,200,00050,900,000q21.3
chr1450,900,00054,100,000q22.1
chr1454,100,00055,500,000q22.2
chr1455,500,00058,100,000q22.3
chr1458,100,00062,100,000q23.1
chr1462,100,00064,800,000q23.2
chr1464,800,00067,900,000q23.3
chr1467,900,00070,200,000q24.1
chr1470,200,00073,800,000q24.2
chr1473,800,00079,300,000q24.3
chr1479,300,00083,600,000q31.1
chr1483,600,00084,900,000q31.2
chr1484,900,00089,800,000q31.3
chr1489,800,00091,900,000q32.11
chr1491,900,00094,700,000q32.12
chr1494,700,00096,300,000q32.13
chr1496,300,000101,400,000q32.2
chr14101,400,000103,200,000q32.31
chr14103,200,000104,000,000q32.32
chr14104,000,000107,349,540q32.33
chr1503,900,000p13
chr153,900,0008,700,000p12
chr158,700,00015,800,000p11.2
chr1515,800,00019,000,000p11.1
chr1519,000,00020,700,000q11.1
chr1520,700,00025,700,000q11.2
chr1525,700,00028,100,000q12
chr1528,100,00030,300,000q13.1
chr1530,300,00031,200,000q13.2
chr1531,200,00033,600,000q13.3
chr1533,600,00040,100,000q14
chr1540,100,00042,800,000q15.1
chr1542,800,00043,600,000q15.2
chr1543,600,00044,800,000q15.3
chr1544,800,00049,500,000q21.1
chr1549,500,00052,900,000q21.2
chr1552,900,00059,100,000q21.3
chr1559,100,00059,300,000q22.1
chr1559,300,00063,700,000q22.2
chr1563,700,00067,200,000q22.31
chr1567,200,00067,300,000q22.32
chr1567,300,00067,500,000q22.33
chr1567,500,00072,700,000q23
chr1572,700,00075,200,000q24.1
chr1575,200,00076,600,000q24.2
chr1576,600,00078,300,000q24.3
chr1578,300,00081,700,000q25.1
chr1581,700,00085,200,000q25.2
chr1585,200,00089,100,000q25.3
chr1589,100,00094,300,000q26.1
chr1594,300,00098,500,000q26.2
chr1598,500,000102,531,392q26.3
chr1607,900,000p13.3
chr167,900,00010,500,000p13.2
chr1610,500,00012,600,000p13.13
chr1612,600,00014,800,000p13.12
chr1614,800,00016,800,000p13.11
chr1616,800,00021,200,000p12.3
chr1621,200,00024,200,000p12.2
chr1624,200,00028,100,000p12.1
chr1628,100,00034,600,000p11.2
chr1634,600,00036,600,000p11.1
chr1636,600,00038,600,000q11.1
chr1638,600,00047,000,000q11.2
chr1647,000,00052,600,000q12.1
chr1652,600,00056,700,000q12.2
chr1656,700,00057,400,000q13
chr1657,400,00066,700,000q21
chr1666,700,00070,800,000q22.1
chr1670,800,00072,900,000q22.2
chr1672,900,00074,100,000q22.3
chr1674,100,00079,200,000q23.1
chr1679,200,00081,700,000q23.2
chr1681,700,00084,200,000q23.3
chr1684,200,00087,100,000q24.1
chr1687,100,00088,700,000q24.2
chr1688,700,00090,354,753q24.3
chr1703,300,000p13.3
chr173,300,0006,500,000p13.2
chr176,500,00010,700,000p13.1
chr1710,700,00016,000,000p12
chr1716,000,00022,200,000p11.2
chr1722,200,00024,000,000p11.1
chr1724,000,00025,800,000q11.1
chr1725,800,00031,800,000q11.2
chr1731,800,00038,100,000q12
chr1738,100,00038,400,000q21.1
chr1738,400,00040,900,000q21.2
chr1740,900,00044,900,000q21.31
chr1744,900,00047,400,000q21.32
chr1747,400,00050,200,000q21.33
chr1750,200,00057,600,000q22
chr1757,600,00058,300,000q23.1
chr1758,300,00061,100,000q23.2
chr1761,100,00062,600,000q23.3
chr1762,600,00064,200,000q24.1
chr1764,200,00067,100,000q24.2
chr1767,100,00070,900,000q24.3
chr1770,900,00074,800,000q25.1
chr1774,800,00075,300,000q25.2
chr1775,300,00081,195,210q25.3
chr1802,900,000p11.32
chr182,900,0007,100,000p11.31
chr187,100,0008,500,000p11.23
chr188,500,00010,900,000p11.22
chr1810,900,00015,400,000p11.21
chr1815,400,00017,200,000p11.1
chr1817,200,00019,000,000q11.1
chr1819,000,00025,000,000q11.2
chr1825,000,00032,700,000q12.1
chr1832,700,00037,200,000q12.2
chr1837,200,00043,500,000q12.3
chr1843,500,00048,200,000q21.1
chr1848,200,00053,800,000q21.2
chr1853,800,00056,200,000q21.31
chr1856,200,00059,000,000q21.32
chr1859,000,00061,600,000q21.33
chr1861,600,00066,800,000q22.1
chr1866,800,00068,700,000q22.2
chr1868,700,00073,100,000q22.3
chr1873,100,00078,077,248q23
chr1906,900,000p13.3
chr196,900,00013,900,000p13.2
chr1913,900,00014,000,000p13.13
chr1914,000,00016,300,000p13.12
chr1916,300,00020,000,000p13.11
chr1920,000,00024,400,000p12
chr1924,400,00026,500,000p11
chr1926,500,00028,600,000q11
chr1928,600,00032,400,000q12
chr1932,400,00035,500,000q13.11
chr1935,500,00038,300,000q13.12
chr1938,300,00038,700,000q13.13
chr1938,700,00043,400,000q13.2
chr1943,400,00045,200,000q13.31
chr1945,200,00048,000,000q13.32
chr1948,000,00051,400,000q13.33
chr1951,400,00053,600,000q13.41
chr1953,600,00056,300,000q13.42
chr1956,300,00059,128,983q13.43
chr204,400,000p25.3
chr24,400,0007,100,000p25.2
chr27,100,00012,200,000p25.1
chr212,200,00016,700,000p24.3
chr216,700,00019,200,000p24.2
chr219,200,00024,000,000p24.1
chr224,000,00027,900,000p23.3
chr227,900,00030,000,000p23.2
chr230,000,00032,100,000p23.1
chr232,100,00036,600,000p22.3
chr236,600,00038,600,000p22.2
chr238,600,00041,800,000p22.1
chr241,800,00047,800,000p21
chr247,800,00052,900,000p16.3
chr252,900,00055,000,000p16.2
chr255,000,00061,300,000p16.1
chr261,300,00064,100,000p15
chr264,100,00068,600,000p14
chr268,600,00071,500,000p13.3
chr271,500,00073,500,000p13.2
chr273,500,00075,000,000p13.1
chr275,000,00083,300,000p12
chr283,300,00090,500,000p11.2
chr290,500,00093,300,000p11.1
chr293,300,00096,800,000q11.1
chr296,800,000102,700,000q11.2
chr2102,700,000106,000,000q12.1
chr2106,000,000107,500,000q12.2
chr2107,500,000110,200,000q12.3
chr2110,200,000114,400,000q13
chr2114,400,000118,800,000q14.1
chr2118,800,000122,400,000q14.2
chr2122,400,000129,900,000q14.3
chr2129,900,000132,500,000q21.1
chr2132,500,000135,100,000q21.2
chr2135,100,000136,800,000q21.3
chr2136,800,000142,200,000q22.1
chr2142,200,000144,100,000q22.2
chr2144,100,000148,700,000q22.3
chr2148,700,000149,900,000q23.1
chr2149,900,000150,500,000q23.2
chr2150,500,000154,900,000q23.3
chr2154,900,000159,800,000q24.1
chr2159,800,000163,700,000q24.2
chr2163,700,000169,700,000q24.3
chr2169,700,000178,000,000q31.1
chr2178,000,000180,600,000q31.2
chr2180,600,000183,000,000q31.3
chr2183,000,000189,400,000q32.1
chr2189,400,000191,900,000q32.2
chr2191,900,000197,400,000q32.3
chr2197,400,000203,300,000q33.1
chr2203,300,000204,900,000q33.2
chr2204,900,000209,000,000q33.3
chr2209,000,000215,300,000q34
chr2215,300,000221,500,000q35
chr2221,500,000225,200,000q36.1
chr2225,200,000226,100,000q36.2
chr2226,100,000231,000,000q36.3
chr2231,000,000235,600,000q37.1
chr2235,600,000237,300,000q37.2
chr2237,300,000243,199,373q37.3
chr2005,100,000p13
chr205,100,0009,200,000p12.3
chr209,200,00012,100,000p12.2
chr2012,100,00017,900,000p12.1
chr2017,900,00021,300,000p11.23
chr2021,300,00022,300,000p11.22
chr2022,300,00025,600,000p11.21
chr2025,600,00027,500,000p11.1
chr2027,500,00029,400,000q11.1
chr2029,400,00032,100,000q11.21
chr2032,100,00034,400,000q11.22
chr2034,400,00037,600,000q11.23
chr2037,600,00041,700,000q12
chr2041,700,00042,100,000q13.11
chr2042,100,00046,400,000q13.12
chr2046,400,00049,800,000q13.13
chr2049,800,00055,000,000q13.2
chr2055,000,00056,500,000q13.31
chr2056,500,00058,400,000q13.32
chr2058,400,00063,025,520q13.33
chr2102,800,000p13
chr212,800,0006,800,000p12
chr216,800,00010,900,000p11.2
chr2110,900,00013,200,000p11.1
chr2113,200,00014,300,000q11.1
chr2114,300,00016,400,000q11.2
chr2116,400,00024,000,000q21.1
chr2124,000,00026,800,000q21.2
chr2126,800,00031,500,000q21.3
chr2131,500,00035,800,000q22.11
chr2135,800,00037,800,000q22.12
chr2137,800,00039,700,000q22.13
chr2139,700,00042,600,000q22.2
chr2142,600,00048,129,895q22.3
chr2203,800,000p13
chr223,800,0008,300,000p12
chr228,300,00012,200,000p11.2
chr2212,200,00014,700,000p11.1
chr2214,700,00017,900,000q11.1
chr2217,900,00022,200,000q11.21
chr2222,200,00023,500,000q11.22
chr2223,500,00025,900,000q11.23
chr2225,900,00029,600,000q12.1
chr2229,600,00032,200,000q12.2
chr2232,200,00037,600,000q12.3
chr2237,600,00041,000,000q13.1
chr2241,000,00044,200,000q13.2
chr2244,200,00048,400,000q13.31
chr2248,400,00049,400,000q13.32
chr2249,400,00051,304,566q13.33
chr302,800,000p26.3
chr32,800,0004,000,000p26.2
chr34,000,0008,700,000p26.1
chr38,700,00011,800,000p25.3
chr311,800,00013,300,000p25.2
chr313,300,00016,400,000p25.1
chr316,400,00023,900,000p24.3
chr323,900,00026,400,000p24.2
chr326,400,00030,900,000p24.1
chr330,900,00032,100,000p23
chr332,100,00036,500,000p22.3
chr336,500,00039,400,000p22.2
chr339,400,00043,700,000p22.1
chr343,700,00044,100,000p21.33
chr344,100,00044,200,000p21.32
chr344,200,00050,600,000p21.31
chr350,600,00052,300,000p21.2
chr352,300,00054,400,000p21.1
chr354,400,00058,600,000p14.3
chr358,600,00063,700,000p14.2
chr363,700,00069,800,000p14.1
chr369,800,00074,200,000p13
chr374,200,00079,800,000p12.3
chr379,800,00083,500,000p12.2
chr383,500,00087,200,000p12.1
chr387,200,00087,900,000p11.2
chr387,900,00091,000,000p11.1
chr391,000,00093,900,000q11.1
chr393,900,00098,300,000q11.2
chr398,300,000100,000,000q12.1
chr3100,000,000100,900,000q12.2
chr3100,900,000102,800,000q12.3
chr3102,800,000106,200,000q13.11
chr3106,200,000107,900,000q13.12
chr3107,900,000111,300,000q13.13
chr3111,300,000113,500,000q13.2
chr3113,500,000117,300,000q13.31
chr3117,300,000119,000,000q13.32
chr3119,000,000121,900,000q13.33
chr3121,900,000123,800,000q21.1
chr3123,800,000125,800,000q21.2
chr3125,800,000129,200,000q21.3
chr3129,200,000133,700,000q22.1
chr3133,700,000135,700,000q22.2
chr3135,700,000138,700,000q22.3
chr3138,700,000142,800,000q23
chr3142,800,000148,900,000q24
chr3148,900,000152,100,000q25.1
chr3152,100,000155,000,000q25.2
chr3155,000,000157,000,000q25.31
chr3157,000,000159,000,000q25.32
chr3159,000,000160,700,000q25.33
chr3160,700,000167,600,000q26.1
chr3167,600,000170,900,000q26.2
chr3170,900,000175,700,000q26.31
chr3175,700,000179,000,000q26.32
chr3179,000,000182,700,000q26.33
chr3182,700,000184,500,000q27.1
chr3184,500,000186,000,000q27.2
chr3186,000,000187,900,000q27.3
chr3187,900,000192,300,000q28
chr3192,300,000198,022,430q29
chr404,500,000p16.3
chr44,500,0006,000,000p16.2
chr46,000,00011,300,000p16.1
chr411,300,00015,200,000p15.33
chr415,200,00017,800,000p15.32
chr417,800,00021,300,000p15.31
chr421,300,00027,700,000p15.2
chr427,700,00035,800,000p15.1
chr435,800,00041,200,000p14
chr441,200,00044,600,000p13
chr444,600,00048,200,000p12
chr448,200,00050,400,000p11
chr450,400,00052,700,000q11
chr452,700,00059,500,000q12
chr459,500,00066,600,000q13.1
chr466,600,00070,500,000q13.2
chr470,500,00076,300,000q13.3
chr476,300,00078,900,000q21.1
chr478,900,00082,400,000q21.21
chr482,400,00084,100,000q21.22
chr484,100,00086,900,000q21.23
chr486,900,00088,000,000q21.3
chr488,000,00093,700,000q22.1
chr493,700,00095,100,000q22.2
chr495,100,00098,800,000q22.3
chr498,800,000101,100,000q23
chr4101,100,000107,700,000q24
chr4107,700,000114,100,000q25
chr4114,100,000120,800,000q26
chr4120,800,000123,800,000q27
chr4123,800,000128,800,000q28.1
chr4128,800,000131,100,000q28.2
chr4131,100,000139,500,000q28.3
chr4139,500,000141,500,000q31.1
chr4141,500,000146,800,000q31.21
chr4146,800,000148,500,000q31.22
chr4148,500,000151,100,000q31.23
chr4151,100,000155,600,000q31.3
chr4155,600,000161,800,000q32.1
chr4161,800,000164,500,000q32.2
chr4164,500,000170,100,000q32.3
chr4170,100,000171,900,000q33
chr4171,900,000176,300,000q34.1
chr4176,300,000177,500,000q34.2
chr4177,500,000183,200,000q34.3
chr4183,200,000187,100,000q35.1
chr4187,100,000191,154,276q35.2
chr504,500,000p15.33
chr54,500,0006,300,000p15.32
chr56,300,0009,800,000p15.31
chr59,800,00015,000,000p15.2
chr515,000,00018,400,000p15.1
chr518,400,00023,300,000p14.3
chr523,300,00024,600,000p14.2
chr524,600,00028,900,000p14.1
chr528,900,00033,800,000p13.3
chr533,800,00038,400,000p13.2
chr538,400,00042,500,000p13.1
chr542,500,00046,100,000p12
chr546,100,00048,400,000p11
chr548,400,00050,700,000q11.1
chr550,700,00058,900,000q11.2
chr558,900,00062,900,000q12.1
chr562,900,00063,200,000q12.2
chr563,200,00066,700,000q12.3
chr566,700,00068,400,000q13.1
chr568,400,00073,300,000q13.2
chr573,300,00076,900,000q13.3
chr576,900,00081,400,000q14.1
chr581,400,00082,800,000q14.2
chr582,800,00092,300,000q14.3
chr592,300,00098,200,000q15
chr598,200,000102,800,000q21.1
chr5102,800,000104,500,000q21.2
chr5104,500,000109,600,000q21.3
chr5109,600,000111,500,000q22.1
chr5111,500,000113,100,000q22.2
chr5113,100,000115,200,000q22.3
chr5115,200,000121,400,000q23.1
chr5121,400,000127,300,000q23.2
chr5127,300,000130,600,000q23.3
chr5130,600,000136,200,000q31.1
chr5136,200,000139,500,000q31.2
chr5139,500,000144,500,000q31.3
chr5144,500,000149,800,000q32
chr5149,800,000152,700,000q33.1
chr5152,700,000155,700,000q33.2
chr5155,700,000159,900,000q33.3
chr5159,900,000168,500,000q34
chr5168,500,000172,800,000q35.1
chr5172,800,000176,600,000q35.2
chr5176,600,000180,915,260q35.3
chr602,300,000p25.3
chr62,300,0004,200,000p25.2
chr64,200,0007,100,000p25.1
chr67,100,00010,600,000p24.3
chr610,600,00011,600,000p24.2
chr611,600,00013,400,000p24.1
chr613,400,00015,200,000p23
chr615,200,00025,200,000p22.3
chr625,200,00027,000,000p22.2
chr627,000,00030,400,000p22.1
chr630,400,00032,100,000p21.33
chr632,100,00033,500,000p21.32
chr633,500,00036,600,000p21.31
chr636,600,00040,500,000p21.2
chr640,500,00046,200,000p21.1
chr646,200,00051,800,000p12.3
chr651,800,00052,900,000p12.2
chr652,900,00057,000,000p12.1
chr657,000,00058,700,000p11.2
chr658,700,00061,000,000p11.1
chr661,000,00063,300,000q11.1
chr663,300,00063,400,000q11.2
chr663,400,00070,000,000q12
chr670,000,00075,900,000q13
chr675,900,00083,900,000q14.1
chr683,900,00084,900,000q14.2
chr684,900,00088,000,000q14.3
chr688,000,00093,100,000q15
chr693,100,00099,500,000q16.1
chr699,500,000100,600,000q16.2
chr6100,600,000105,500,000q16.3
chr6105,500,000114,600,000q21
chr6114,600,000118,300,000q22.1
chr6118,300,000118,500,000q22.2
chr6118,500,000126,100,000q22.31
chr6126,100,000127,100,000q22.32
chr6127,100,000130,300,000q22.33
chr6130,300,000131,200,000q23.1
chr6131,200,000135,200,000q23.2
chr6135,200,000139,000,000q23.3
chr6139,000,000142,800,000q24.1
chr6142,800,000145,600,000q24.2
chr6145,600,000149,000,000q24.3
chr6149,000,000152,500,000q25.1
chr6152,500,000155,500,000q25.2
chr6155,500,000161,000,000q25.3
chr6161,000,000164,500,000q26
chr6164,500,000171,115,067q27
chr702,800,000p22.3
chr72,800,0004,500,000p22.2
chr74,500,0007,300,000p22.1
chr77,300,00013,800,000p21.3
chr713,800,00016,500,000p21.2
chr716,500,00020,900,000p21.1
chr720,900,00025,500,000p15.3
chr725,500,00028,000,000p15.2
chr728,000,00028,800,000p15.1
chr728,800,00035,000,000p14.3
chr735,000,00037,200,000p14.2
chr737,200,00043,300,000p14.1
chr743,300,00045,400,000p13
chr745,400,00049,000,000p12.3
chr749,000,00050,500,000p12.2
chr750,500,00054,000,000p12.1
chr754,000,00058,000,000p11.2
chr758,000,00059,900,000p11.1
chr759,900,00061,700,000q11.1
chr761,700,00067,000,000q11.21
chr767,000,00072,200,000q11.22
chr772,200,00077,500,000q11.23
chr777,500,00086,400,000q21.11
chr786,400,00088,200,000q21.12
chr788,200,00091,100,000q21.13
chr791,100,00092,800,000q21.2
chr792,800,00098,000,000q21.3
chr798,000,000103,800,000q22.1
chr7103,800,000104,500,000q22.2
chr7104,500,000107,400,000q22.3
chr7107,400,000114,600,000q31.1
chr7114,600,000117,400,000q31.2
chr7117,400,000121,100,000q31.31
chr7121,100,000123,800,000q31.32
chr7123,800,000127,100,000q31.33
chr7127,100,000129,200,000q32.1
chr7129,200,000130,400,000q32.2
chr7130,400,000132,600,000q32.3
chr7132,600,000138,200,000q33
chr7138,200,000143,100,000q34
chr7143,100,000147,900,000q35
chr7147,900,000152,600,000q36.1
chr7152,600,000155,100,000q36.2
chr7155,100,000159,138,663q36.3
chr802,200,000p23.3
chr82,200,0006,200,000p23.2
chr86,200,00012,700,000p23.1
chr812,700,00019,000,000p22
chr819,000,00023,300,000p21.3
chr823,300,00027,400,000p21.2
chr827,400,00028,800,000p21.1
chr828,800,00036,500,000p12
chr836,500,00038,300,000p11.23
chr838,300,00039,700,000p11.22
chr839,700,00043,100,000p11.21
chr843,100,00045,600,000p11.1
chr845,600,00048,100,000q11.1
chr848,100,00052,200,000q11.21
chr852,200,00052,600,000q11.22
chr852,600,00055,500,000q11.23
chr855,500,00061,600,000q12.1
chr861,600,00062,200,000q12.2
chr862,200,00066,000,000q12.3
chr866,000,00068,000,000q13.1
chr868,000,00070,500,000q13.2
chr870,500,00073,900,000q13.3
chr873,900,00078,300,000q21.11
chr878,300,00080,100,000q21.12
chr880,100,00084,600,000q21.13
chr884,600,00086,900,000q21.2
chr886,900,00093,300,000q21.3
chr893,300,00099,000,000q22.1
chr899,000,000101,600,000q22.2
chr8101,600,000106,200,000q22.3
chr8106,200,000110,500,000q23.1
chr8110,500,000112,100,000q23.2
chr8112,100,000117,700,000q23.3
chr8117,700,000119,200,000q24.11
chr8119,200,000122,500,000q24.12
chr8122,500,000127,300,000q24.13
chr8127,300,000131,500,000q24.21
chr8131,500,000136,400,000q24.22
chr8136,400,000139,900,000q24.23
chr8139,900,000146,364,022q24.3
chr902,200,000p24.3
chr92,200,0004,600,000p24.2
chr94,600,0009,000,000p24.1
chr99,000,00014,200,000p23
chr914,200,00016,600,000p22.3
chr916,600,00018,500,000p22.2
chr918,500,00019,900,000p22.1
chr919,900,00025,600,000p21.3
chr925,600,00028,000,000p21.2
chr928,000,00033,200,000p21.1
chr933,200,00036,300,000p13.3
chr936,300,00038,400,000p13.2
chr938,400,00041,000,000p13.1
chr941,000,00043,600,000p12
chr943,600,00047,300,000p11.2
chr947,300,00049,000,000p11.1
chr949,000,00050,700,000q11
chr950,700,00065,900,000q12
chr965,900,00068,700,000q13
chr968,700,00072,200,000q21.11
chr972,200,00074,000,000q21.12
chr974,000,00079,200,000q21.13
chr979,200,00081,100,000q21.2
chr981,100,00084,100,000q21.31
chr984,100,00086,900,000q21.32
chr986,900,00090,400,000q21.33
chr990,400,00091,800,000q22.1
chr991,800,00093,900,000q22.2
chr993,900,00096,600,000q22.31
chr996,600,00099,300,000q22.32
chr999,300,000102,600,000q22.33
chr9102,600,000108,200,000q31.1
chr9108,200,000111,300,000q31.2
chr9111,300,000114,900,000q31.3
chr9114,900,000117,700,000q32
chr9117,700,000122,500,000q33.1
chr9122,500,000125,800,000q33.2
chr9125,800,000130,300,000q33.3
chr9130,300,000133,500,000q34.11
chr9133,500,000134,000,000q34.12
chr9134,000,000135,900,000q34.13
chr9135,900,000137,400,000q34.2
chr9137,400,000141,213,431q34.3
chrX04,300,000p22.33
chrX4,300,0006,000,000p22.32
chrX6,000,0009,500,000p22.31
chrX9,500,00017,100,000p22.2
chrX17,100,00019,300,000p22.13
chrX19,300,00021,900,000p22.12
chrX21,900,00024,900,000p22.11
chrX24,900,00029,300,000p21.3
chrX29,300,00031,500,000p21.2
chrX31,500,00037,600,000p21.1
chrX37,600,00042,400,000p11.4
chrX42,400,00046,400,000p11.3
chrX46,400,00049,800,000p11.23
chrX49,800,00054,800,000p11.22
chrX54,800,00058,100,000p11.21
chrX58,100,00060,600,000p11.1
chrX60,600,00063,000,000q11.1
chrX63,000,00064,600,000q11.2
chrX64,600,00067,800,000q12
chrX67,800,00071,800,000q13.1
chrX71,800,00073,900,000q13.2
chrX73,900,00076,000,000q13.3
chrX76,000,00084,600,000q21.1
chrX84,600,00086,200,000q21.2
chrX86,200,00091,800,000q21.31
chrX91,800,00093,500,000q21.32
chrX93,500,00098,300,000q21.33
chrX98,300,000102,600,000q22.1
chrX102,600,000103,700,000q22.2
chrX103,700,000108,700,000q22.3
chrX108,700,000116,500,000q23
chrX116,500,000120,900,000q24
chrX120,900,000128,700,000q25
chrX128,700,000130,400,000q26.1
chrX130,400,000133,600,000q26.2
chrX133,600,000138,000,000q26.3
chrX138,000,000140,300,000q27.1
chrX140,300,000142,100,000q27.2
chrX142,100,000147,100,000q27.3
chrX147,100,000155,270,560q28
chrY02,500,000p11.32
chrY2,500,0003,000,000p11.31
chrY3,000,00011,600,000p11.2
chrY11,600,00012,500,000p11.1
chrY12,500,00013,400,000q11.1
chrY13,400,00015,100,000q11.21
chrY15,100,00019,800,000q11.221
chrY19,800,00022,100,000q11.222
chrY22,100,00026,200,000q11.223
chrY26,200,00028,800,000q11.23
chrY28,800,00059,373,566q12

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